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ANDROGENETIC ALOPECIA (PATTERN HAIR LOSS)

May 26, 2016

Androgenetic alopecia (pattern hair loss)

    AGA or pattern hair loss is the most common hair loss in men and women. Clinical characteristics include a reduction of terminal hair density on the scalp that follows a typical pattern in both genders, with a conversion of terminal to vellus-like hairs and an increase of telogen hair (in an episode of active shedding).

    Male pattern hair loss results from a combination of androgen and genetics. Its pattern will develop with recession of the frontal hairline to M-shaped and can be classified by Norwood-Hamilton classification. Ethnic variation in the incidence has been reported. Caucasian has higher incidence than Asian and African.

    Female pattern is age-related. 40% of Caucasian women have developed some degree of this hair loss at age 70 but less frequent in Asian women, presented with a diffuse loss of hair on the crown and persistence of the frontal hairline.

     Patient history and physical exam usually give a definite diagnosis. In young women, further investigations are recommended to rule out other diseases.

     Currently, two medications are approved for the treatment of AGA: oral finasteride and topical minoxidail. However, hair restoration or hair transplantation is the most successful and permanent treatment for AGA.

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